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Heat shock protein
The HSR provides cells with an enhanced ability to e The functions and regulation of heat shock proteins; key orchestrators of proteostasis and the heat shock response | SpringerLink. Purpose of review: Heat shock protein 90 (Hsp90) is a molecular chaperone required for the stability and function of a number of conditionally activated and/or expressed signaling proteins, as well as multiple mutated, chimeric, or overexpressed signaling proteins, which promote cancer cell growth or survival or both. They were first described in relation to heat shock , [1] but are now known to also be expressed during other stresses including exposure to cold, [2] UV light [3] and during wound healing or tissue remodeling.
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